Thursday 6 December 2018

Isopropyl Alcohol



Isopropyl Alcohol

Alexis Bell



Figure 1. Isopropyl Alcohol Ignition.


Isopropyl alcohol, or “isopropanol,” is a chemical with a characteristic odor and colourless appearance, and is the active ingredient in (most) rubbing alcohols.1 Despite the unsettling odor of this compound, it has many uses besides rubbing alcohol, including: denaturant, anti-freeze, preservative, and even food flavouring.1 It is also used to produce acetone, a chemical that is the main ingredient in most nail polish removers.1
Isopropanol is so common in household products, that it can be found in various products for personal care (cosmetics, soaps), cleaning (glass cleaners), and interior design (paints, varnishes).1 This wide use is due to isopropanol’s versatility as a solvent. Unlike water, isopropanol can dissolve non-polar molecules, like oil.2 This means it can reliably clean oil traces from surfaces, as well as dissolve non-polar compounds in various products.2 This is because it has both non-polar (isopropyl) and polar (hydroxyl) groups present.1 This just means that it can dissolve polar and non-polar compounds, because the overall polarity is better balanced than in other solvents. Basically, it is a “happy medium” of alcohol solvents.
            Isopropanol is a relatively safe chemical, but like most alcohols, it is flammable.3 Not only is isopropyl alcohol flammable, but it also is heavier than air in gaseous state.1 Therefore, it can sink below air, which means it can be ignited from a distant source.1 This is because it can spread more quickly below air (and without disruption from wind), so the spark has more potential to ignite a fire.1 It is also explosive in air.1
            Despite the flammability risk of isopropanol, it is relatively non-toxic. It is less toxic than methanol, another commonly used organic solvent.2 It is also one of the least toxic options in biological specimen preservation.2 Formaldehyde and other synthetic compounds are common in the biology laboratory, and can cause various negative health effects.2 Isopropanol is a safer alternative to these chemicals.2 It is also unclassified as a cancer or reproductive risk, however, it can cause Fetal Alcohol Spectrum Disorder when ingested by expectant mothers.1
Perhaps the widest known use of isopropanol is that it acts as an antimicrobial, antiseptic, and disinfectant.2 This means it can effectively clean microbes and bacteria from inanimate (non-living) and animate (living) surfaces.3 This is the most common use of rubbing alcohol. Rubbing alcohol can be used to disinfect or reduce bacteria on household surfaces, personal care items, and surface wounds.3 However, rubbing alcohol cannot sterilize items (eradicate disease-causing agents) and is ineffective against resistant strains of bacteria and viruses.3

Figure 2. Isopropyl Alcohol and Mesoft Swabs.

Source: Isopropanol and Mesoft Swabs. https://www.flickr.com/photos/maraker/14157327478/in/photolist-Xn1Lax-8mQSuu-bNknmF-hXGFNc-nz31e5-nPC9f1-dBGiHt-MvKxmo-akkLqt-akkLik-UkYLT5-3S5WZ-51qygA by Ã…kerfelt, M. is licensed under CC BY 2.0. (accessed December 6, 2018).

            Overall, isopropyl alcohol is a relatively safe compound, with many beneficial uses in household products, medicine, and manufacturing. When used cautiously, it poses little risk to consumer health, while preventing additional risks from alternatives with higher toxicity.



References
1Canadian Centre for Occupational Health and Safety. 2-Propanol, 2008, CHEMINFO.
 26, 2018).
2Isopropyl Alcohol. Wikipedia. https://en.wikipedia.org/wiki/Isopropyl_alcohol (accessed Nov    
             28, 2018).
3University of Kentucky Biological Safety. Laboratory Disinfectants.
             https://ehs.uky.edu/docs/pdf/bio_laboratory_disinfectants_0001.pdf (accessed Nov 28,   
             2018).

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